| CAS ID | 133310-19-7 |
|---|---|
| IUPAC Name | Lamotrigine N2-Glucuronide |
| Molecular Formula | C15H16Cl2N5O6+ |
| Molecular Weight | |
| SMILES | OC(=O)[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)[N+]2=[13C](N=[13C]([13C](=N2)C3=C(C(=CC=C3)Cl)Cl)N)N |
| CAS ID | 133310-19-7 |
|---|---|
| IUPAC Name | Lamotrigine N2-Glucuronide |
| Molecular Formula | C15H16Cl2N5O6+ |
| Molecular Weight | |
| SMILES | OC(=O)[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)[N+]2=[13C](N=[13C]([13C](=N2)C3=C(C(=CC=C3)Cl)Cl)N)N |
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Lamotrigine n2 glucuronide is a primary metabolite of lamotrigine, formed through glucuronidation in the liver. It affects drug metabolism and excretion, therefore affecting the pharmacokinetics of lamotrigine in medicinal uses.
The lamotrigine n2 glucuronide melting point is not widely documented due to its nature as a glucuronide conjugate. For pharmacokinetic and analytical research, its solubility and stability in aqueous solutions are more important.
The chemical formula of lamotrigine n2 glucuronide is C15H15Cl2N5O6. In this form, lamotrigine is conjugated with glucuronic acid, which helps it be eliminated from the body via renal excretion.
Mass spectrometry, nuclear magnetic resonance (NMR), and high-performance liquid chromatography (HPLC) are used to examine the chemical structure of Lamotrigine n2 glucuronide to validate its molecular composition and metabolic routes.
Lamotrigine n2 glucuronide is crucial in pharmacology as it affects lamotrigine clearance and drug interactions. Understanding its metabolism helps patients on lamotrigine medication maximize therapeutic results, reduce toxicity, and optimize dosage.
