CAS ID | 9063-38-1 |
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IUPAC Name | Sodium Starch Glycolate |
Molecular Formula | N/A |
Molecular Weight | |
SMILES | (3S,6R)-2-(hydroxymethyl)-6-[(3R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrate |
CAS ID | 9063-38-1 |
---|---|
IUPAC Name | Sodium Starch Glycolate |
Molecular Formula | N/A |
Molecular Weight | |
SMILES | (3S,6R)-2-(hydroxymethyl)-6-[(3R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrate |
Sodium starch glycolate is a pharmaceutical excipient often used as a disintegrant in tablet and capsule formulations. It helps tablets break down into tiny particles in the gastrointestinal system, resulting in quicker medication solubility and absorption. The pharmaceutical industry highly regards this chemical due to its efficacy and safety profile.
The sodium starch glycolate structure is built on a modified starch backbone. It is made up of cross-linked sodium carboxymethyl groups connected to starch polymers. This chemical alteration confers distinctive features, such as great water absorption and swelling capacity, making it an effective disintegrant. The cross-linking guarantees that the material does not entirely disintegrate but expands rapidly when in contact with water.
The chemical formula of sodium starch glycolate is often expressed as:
(C6H9O4Na)n
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Sodium starch glycolate is a popular excipient in pharmaceutical formulations because of its good disintegration capabilities. Its structure and chemical formula (C6H10O5Na) enable quick dissolving and regulated release of active substances.
The sodium starch glycolate structure influences its propensity to absorb water and swell. Because of its chemical composition (C6H10O5Na), tablets disintegrate faster, increasing the bioavailability of active medicinal substances.
The sodium starch glycolate chemical formula, C6H10O5Na, and its molecular structure enable rapid water absorption, a key characteristic contributing to its disintegrant properties.
Sodium starch glycolate's cross-linked starch chains make it a very powerful super disintegrant. This characteristic and its molecular composition (C6H10O5Na) result in fast disintegration in moist environments.
The sodium starch glycolate structure allows for quick water absorption, making it an excellent disintegrant. Its chemical formula (C6H10O5Na) promotes effective breakdown, quicker release and increased bioavailability.